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May 7, 20261 citations

Fatal transfusion-transmitted severe dengue in an immunocompromised host: case report and systematic literature review.

ATAlexandre Mestre TejoHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo ADAmaro Nunes Duarte-NetoHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo JRJacqueline Alves RenaHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Puntos clave

To report a case of fatal transfusion-transmitted severe dengue in an immunocompromised individual and review related literature.
Case report of a stem cell transplant recipient during the 2024 dengue epidemic in Brazil.
Phylogenetic analysis linked the case to the outbreak.
The patient developed severe dengue after transfusion, leading to a fatal outcome.
Phylogenetic linkage confirmed the transmission route as transfusion-related.

Resumen

Transfusion-transmitted dengue remains a relevant risk during outbreaks. We report a transfusion-transmitted severe dengue case in a stem cell transplant recipient during the 2024 epidemic in Brazil, supported by phylogenetic linkage, evolving to a fatal outcome. This sentinel case highlights the potential severity of transfusion-transmitted dengue, particularly in immunocompromised hosts.

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Tejo et al. (Tue,) studied this question.

synapsesocial.com/papers/69fc2c1f8b49bacb8b347b9b https://doi.org/https://doi.org/10.1093/cid/ciag292

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