PURPOSE: To evaluate the clinical, neurological, and neuropsychiatric characteristics, subtype distribution, and multidisciplinary management in patients developing Neuro-Behçet's syndrome (NBS) during follow-up for Behçet uveitis (BU). METHODS: This retrospective study included 12 patients with panuveitis who developed NBS during follow-up for uveitis. Demographic data, ophthalmic findings, neurological and neuropsychiatric manifestations, neuroimaging results, cerebrospinal fluid (CSF) analyses, and treatments were reviewed. Neurological involvement was classified into parenchymal, vascular, neuropsychiatric, and peripheral types. RESULTS: > 0.05) with no permanent neurological sequelae. CONCLUSION: In this uveitis cohort, NBS developed in 4% of patients with BU. Because neurological involvement may occur subclinically or independently of ocular activity, clinicians should maintain a high index of suspicion for neurological and neuropsychiatric manifestations. A prompt multidisciplinary approach and timely treatment escalation are essential to prevent permanent neurological damage in this patient population.
Kaymak et al. (Mon,) studied this question.