High‐dimensionality undersampled patch‐based reconstruction (HD‐PROST) for accelerated multi‐contrast MRI

PURPOSE: To develop a new high-dimensionality undersampled patch-based reconstruction (HD-PROST) for highly accelerated 2D and 3D multi-contrast MRI. METHODS: mapping. Additional in vivo experiments for reconstructing multiple undersampled 3D magnetization transfer (MT)-weighted images were conducted to illustrate the impact of HD-PROST for high-resolution multi-contrast 3D imaging. RESULTS: values of white matter and gray matter were in good agreement with those reported in the literature for MRF acquisitions with reduced number of time point images (500 time point images, ~2.5 s scan time). For in vivo MT-weighted 3D acquisitions (6 different contrasts), HD-PROST achieved similar image quality than the fully sampled reference image for an undersampling factor of 6.5-fold. CONCLUSION: HD-PROST enables multi-contrast 2D and 3D MR images in a short acquisition time without compromising image quality. Ultimately, this technique may increase the potential of conventional parameter mapping.