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Melting away: Phase-change materials (PCMs) are used to encapsulate colloidal particles with FITC-dextran to demonstrate a new temperature-sensitive drug release system. As the temperature is increased to the melting point of the PCM, the particles leach out, followed by release of FITC-dextran. The initiation and rate of release can be manipulated by using different combinations of materials for the PCM and colloidal particles.
Choi et al. (Mon,) studied this question.
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