Antifungal metabolites from Myxococcus stipitatus GXUA 01510 for the control of sugarcane Pokkah boeng disease caused by Fusarium sacchari | Synapse
May 8, 2026Open Access
Antifungal metabolites from Myxococcus stipitatus GXUA 01510 for the control of sugarcane Pokkah boeng disease caused by Fusarium sacchari
Puntos clave
To evaluate the antifungal activity of thiazole compounds against Fusarium sacchari, which causes Pokkah boeng disease in sugarcane.
Evaluated the antifungal metabolites cystothiazole A and melithiazol F against Fusarium sacchari.
Assessed effects on growth, spore germination, and cell membrane integrity of the pathogen.
Cystothiazole A and melithiazol F significantly inhibited Fusarium sacchari growth and spore germination.
Disruption of cell membrane integrity was observed with both thiazole compounds.
Resumen
The thiazole compounds cystothiazole A (7) and melithiazol F (9) potently inhibited Fusarium sacchari by suppressing its growth and spore germination and disrupting cell membrane integrity.