Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

Puntos clave

• This research aims to investigate the role of the loop in the wild-type conformation of coproheme decarboxylase in substrate transfer regulation.
• Analyzing the structural conformation of coproheme decarboxylase from Listeria monocytogenes
• Examining the interaction between active site and cosubstrates
• The loop in wild-type conformation significantly regulates cosubstrate transfer toward coproheme.
• Evidence of the loop's critical role suggests implications for enzymatic function and substrate specificity.

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