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Commentary on “Shifting Paradigm: Utilization and Outcomes with Neoadjuvant Chemotherapy for cT4 and cN2 Colon Cancers” | Synapse
May 8, 2026
Open Access
Commentary on “Shifting Paradigm: Utilization and Outcomes with Neoadjuvant Chemotherapy for cT4 and cN2 Colon Cancers”
CS
Carlo Alberto Schena
Fondazione Poliambulanza Istituto Ospedaliero
LM
Luigi Marano
SA
Sergio Alfieri
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Puntos clave
This commentary evaluates the shifting paradigm in the use of neoadjuvant chemotherapy for advanced colon cancers.
Analysis of existing literature on neoadjuvant chemotherapy utilization for cT4 and cN2 colon cancers.
Evaluation of treatment outcomes and survival rates associated with neoadjuvant chemotherapy.
Emerging evidence suggests improved outcomes with neoadjuvant chemotherapy in cT4 and cN2 cases.
Variability in utilization patterns indicates a need for standardized treatment protocols.
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We find the article by Hartley et al ...
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Schena et al. (Wed,) studied this question.
synapsesocial.com/papers/69fd7f86bfa21ec5bbf080c9
https://doi.org/https://doi.org/10.3390/cancers18091487