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Oxygen isotopic measurements in three Late Quaternary deep-sea cores from the Gulf of Mexico record a major anomaly between about 15,000 and 12,000 years ago superimposed on a more characteristic oceanic oxygen isotopic curve. This resulted from major influx of isotopically light glacial meltwater via the Mississippi River from the disintegrating Late Wisconsin Laurentide Ice Sheet 2000 kilometers to the north.
Kennett et al. (Fri,) studied this question.