August 1, 2014

Enantioselective Formation of All‐Carbon Quaternary Stereocenters from Indoles and Tertiary Alcohols Bearing A Directing Group

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Resumen

Described is an efficient catalytic asymmetric intermolecular C-C bond-formation process to generate acyclic all-carbon quaternary stereocenters. The reactions overcome the unfavorable steric hindrance around reactive centers, and the competitive elimination (E1), to form a range of useful indole products with excellent efficiency and enantioselectivity.

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Cite This Study

Zhao et al. (Fri,) studied this question.

synapsesocial.com/papers/69ffd0e9b124fe581985a18b https://doi.org/https://doi.org/10.1002/anie.201405252

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