Modular assembly of chiral biaryl phosphoramidite (BPA) libraries by nickel catalysis

Puntos clave

• To establish a P(iii)-directed C–H arylation method for the modular assembly of biaryl phosphoramidite libraries.
• Developed a nickel-catalyzed C–H arylation technique.
• Focused on the modular assembly of biaryl phosphoramidite libraries.
• Evaluated efficacy in palladium-catalyzed asymmetric reactions.
• The new method successfully created diverse biaryl phosphoramidite libraries.
• Demonstrated exceptional efficacy in palladium-catalyzed asymmetric reactions.