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January 5, 2009

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Instantaneous Deprotection of Tosylamides and Esters with SmI2/Amine/Water

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Resumen

SmI(2)/amine/water mediates instantaneous cleavage of tosyl amides and tosyl esters. Highly hindered, sensitive and functionalized substrates were successfully deprotected in near quantitative yield.

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Cite This Study

Ankner et al. (Mon,) studied this question.

synapsesocial.com/papers/6a00e565e4618ba4162dc4ac https://doi.org/https://doi.org/10.1021/ol802243d

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Instantaneous Deprotection of Tosylamides and Esters with SmI2/Amine/Water | Synapse