Intratumoral administration of astatine-211-labeled gold nanoparticle for alpha therapy

BACKGROUND: At-AuNP) administered intratumorally. RESULTS: At-AuNP-S-mPEG with a diameter of 5 nm. CONCLUSIONS: At-AuNP-S-mPEG, was shown to suppress the growth of tumor tissue strongly in a particle size-dependent manner without radiation exposure to other organs caused by systemic spread of the radionuclide.