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September 13, 2022International Journal of MS Care3 citationsOpen Access

Outcomes and Health Care Service Use in Adults 50 Years or Older With and Without Multiple Sclerosis: A 6-Year Observational Analysis

LFLéorah FreemanALAshlea LucasJZJia Zhou

Key Result

In adults 50 years or older, having multiple sclerosis was significantly associated with worse health measures compared to matched controls without MS (P<.0001).

Study Design

Type

Observational (n=21,492)

Structured PICO

Does having multiple sclerosis affect outcomes and health care service use in adults 50 years or older compared to matched controls without MS?

P
Population
21,492 adults 50 years or older (10,746 with multiple sclerosis and 10,746 matched controls without MS) from US claims data (IBM-Truven MarketScan commercial and Medicare databases, 2011-2017).
I
Intervention
Multiple sclerosis (aging MS cohort)
C
Comparator
Matched controls without multiple sclerosis
O
Outcome
Outcomes and health care service use

In adults aged 50 and older, having multiple sclerosis is associated with worse health outcomes and increased healthcare service use compared to aging alone.

Main Result

p-value: p=<.0001

Abstract

BACKGROUND: Multiple sclerosis (MS) typically presents in young adulthood. Recent data show the highest prevalence of MS in people aged 55 to 64 years; however, there are limited studies of this population. METHODS: Administrative US claims data from IBM-Truven MarketScan commercial and Medicare databases (2011-2017) were analyzed. People with MS 50 years or older were assigned to the aging MS cohort (n = 10,746). The matched controls were people 50 years or older without MS (n = 10,746). Multivariable models compared outcomes between groups. RESULTS: < .0001). CONCLUSIONS: In people 50 years or older, measures typically associated with worse health primarily resulted from having MS rather than being a consequence of aging alone.

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Cite This Study

Freeman et al. (2022) conducted an observational in Multiple Sclerosis (n=21,492). Multiple Sclerosis vs. Matched controls without MS was evaluated on Outcomes and health care service use (p=<.0001). In adults 50 years or older, having multiple sclerosis was significantly associated with worse health measures compared to matched controls without MS (P<.0001).

synapsesocial.com/papers/6a05017b23c12501a19128f2https://doi.org/10.7224/1537-2073.2021-124
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