What is the clinical evidence from this study?

Study design: Cohort. Population: Critical illness requiring ICU admission (n=5505). Intervention: Oldest-old age (≥90 years) vs. Younger patients. Primary outcome: Total in-hospital mortality (p=.001).

November 17, 2005

Outcome of Critically Ill Oldest‐Old Patients (Aged 90 and Older) Admitted to the Intensive Care Unit

Resultado clave

Critically ill oldest-old patients (≥90 years) had significantly higher in-hospital mortality compared to younger patients (40% vs 8.9%, P=0.001).

Diseño del estudio

Tipo

Cohort (n=5,505)

Multicéntrico

PICO estructurado

Does being in the oldest-old age group (≥90 years) increase in-hospital and ICU mortality in critically ill patients admitted to the ICU compared to younger patients?

Población

5,505 consecutive critically ill patients admitted to a general intensive care unit, including 60 oldest-old patients (aged 90-98) and younger patients, in Athens, Greece.

Intervención

Intensive care unit admission for oldest-old patients (aged ≥90 years)

Comparador

Intensive care unit admission for younger patients

Resultado

In-hospital and ICU mortalityhard clinical

Critically ill patients aged 90 and older have significantly higher in-hospital mortality (40%) than younger patients, though the absolute mortality rate does not necessarily preclude ICU care in this population.

Resultado numérico

Tasa de eventos absoluta: 40% vs 8.9%

valor p: p=.001

Resumen

OBJECTIVES: To compare the outcomes of critically ill oldest-old patients (> or = 90) with those of younger patients. DESIGN: Prospective cohort study. SETTING: General intensive care unit (ICU) of a tertiary care hospital in Athens, Greece. PARTICIPANTS: The oldest-old and younger patients. MEASUREMENTS: In-hospital and ICU mortality and stay, demographics, comorbidity, and complications. RESULTS: Of 5,505 consecutive patients admitted to the ICU, 60 (1.1%) were in the oldest-old group (aged 90-98). Their mean length of ICU and hospital stay+/-standard deviation was 5.3+/-6.8 and 23.3+/-35.7 days, respectively. ICU mortality was 20%. Total in-hospital mortality was 40%, compared with 8.9% (P=.001) in younger patients. Acute Physiology and Chronic Health Evaluation II score was independently associated with in-hospital mortality (odds ratio=1.18, 95% confidence interval=1.05-1.33). Of 24 oldest-old patients who died, 22 (91.7%) died in the ICU or in the ward within 30 days after ICU discharge. CONCLUSION: All-cause in-hospital mortality was higher in the oldest-old group than in younger patients, but the mortality of this cohort of patients did not seem to reach a figure that would make physicians, relatives, and healthcare administrators decide against ICU care in this population.

Preguntar a la IA

Me gusta

Guardar

Preguntar a la IA

Me gusta

Guardar

Cite This Study

Rellos et al. (Thu,) conducted a cohort in Critical illness requiring ICU admission (n=5,505). Oldest-old age (≥90 years) vs. Younger patients was evaluated on Total in-hospital mortality (p=.001). Critically ill oldest-old patients (≥90 years) had significantly higher in-hospital mortality compared to younger patients (40% vs 8.9%, P=0.001).

synapsesocial.com/papers/6a0874721e8b9db648de0bef https://doi.org/https://doi.org/10.1111/j.1532-5415.2005.00544.x

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: