The number of diseased vessels independently predicted the incidence of in-hospital heart failure with preserved ejection fraction (OR 4.108) in patients with acute myocardial infarction.
Observational (n=405)
No
What are the independent predictors and in-hospital outcomes of incident heart failure with preserved ejection fraction (HFpEF) in patients with acute myocardial infarction (AMI) undergoing primary PCI?
In patients with acute myocardial infarction and preserved LVEF, elevated Hs-CRP, NT-proBNP, and multivessel disease independently predict the development of in-hospital HFpEF, which is associated with higher rates of paroxysmal atrial fibrillation.
Estimación del efecto: OR 4.108 (95% CI 1.595-10.578)
valor p: p=0.003
Patients with acute myocardial infarction (AMI) complicated by heart failure with preserved ejection fraction (HFpEF) are likely to have more adverse cardiovascular events and higher mortality. The purpose of this study was to examine the predictors and outcomes in AMI patients complicated by HFpEF.We examined the demographics, clinical data, and clinical outcomes in 405 consecutive subjects who firstly presented with AMI after undergoing emergency percutaneous coronary intervention from January 2013 to June 2016.Three hundred twenty patients and eighty-five patients were classified into the nonheart failure (non-HF) group and HFpEF group, respectively. Patients with HFpEF had higher prevalence of prior hypertension, had higher levels of biomarkers, and had a larger left atrial diameter with a nondilated left ventricle were more likely to develop multivessel disease-vessels and had infarction-related artery located in left anterior descending artery than patients without HF. Moreover, patients with HFpEF had a higher probability of developing the in-hospital incident cardiovascular complications and death than non-HF patients.Two routine biomarkers, levels of hypersensitive C-reactive protein and N-terminal-pro brain natriuretic peptide, and number of diseased-vessels were independent predictors for in-hospital HFpEF incidence in AMI patients with preserved LVEF. AMI patients with HFpEF had a higher probability of in-hospital cardiovascular outcomes and mortality.
Xu et al. (Fri,) conducted a observational in Acute myocardial infarction (n=405). Number of diseased vessels was evaluated on Incidence of in-hospital heart failure with preserved ejection fraction (OR 4.108, 95% CI 1.595-10.578, p=0.003). The number of diseased vessels independently predicted the incidence of in-hospital heart failure with preserved ejection fraction (OR 4.108) in patients with acute myocardial infarction.