Simultaneous hybrid thoracoscopic epicardial and transcatheter endocardial ablation achieved a 67.2% success rate without antiarrhythmic therapy at 23.1 months, with a 20.3% complication rate.
Observational (n=64)
No
Does a simultaneous hybrid thoracoscopic epicardial and transcatheter endocardial ablation provide effective rhythm control in patients with persistent and long-standing persistent atrial fibrillation?
Hybrid epicardial and endocardial ablation for persistent and long-standing persistent AF offers reasonable midterm rhythm control (67.2% success) but is associated with a non-negligible 20.3% complication rate.
AIMS: The purpose of this study was to analyse the efficacy and complication rates of the simultaneous hybrid procedure in a series of patients with persistent and long-standing persistent atrial fibrillation (AF) in a midterm follow-up. METHODS AND RESULTS: Sixty-four consecutive patients (56 males, 59.7 ± 8.7 years) having undergone isolation of pulmonary veins (PVs) and posterior wall of left atrium (LA) by means of hybrid thoracoscopic ablation for symptomatic persistent (n = 21, 33%) and long-standing persistent AF (n = 43, 67%) were analysed. At a mean follow-up of 23.1 ± 14.1 months (median 21; range 6-57), the success rate without antiarrhythmic therapy was achieved in 67.2% of patients. Procedure-related complications were observed in 13 patients (20.3%) including 2 LA perforations (3.1%) requiring, respectively, conversion to sternotomy and small left-sided thoracotomy. The success rate did not significantly differ between persistent and long-standing persistent AF (respectively, 71.4 and 65.1%; P = 0.4). Patients with AF relapse during the blanking period were 4.60 times more likely to have AF recurrence after 3 months from the ablation procedure. CONCLUSION: The hybrid procedure yields promising results in the setting of both persistent and long-standing persistent AF after midterm follow-up, at the expense of a non-negligible rate of adverse events. Our findings need to be confirmed by further larger and prospective studies.
Asmundis et al. (Tue,) conducted a observational in Persistent and long-standing persistent atrial fibrillation (n=64). Simultaneous hybrid thoracoscopic epicardial and transcatheter endocardial ablation was evaluated on Success rate without antiarrhythmic therapy. Simultaneous hybrid thoracoscopic epicardial and transcatheter endocardial ablation achieved a 67.2% success rate without antiarrhythmic therapy at 23.1 months, with a 20.3% complication rate.
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