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The goal of this section is to define the optimal method(s) of detecting colon dysplasia in patients with IBD. Detection of dysplasia, which is the immediate goal of surveillance colonoscopy, was chosen as the primary endpoint, with the understanding that detection of dysplasia is not clearly documented to improve clinical outcomes such as CRC incidence or mortality. Only histologic diagnoses of lowgrade or high-grade dysplasia were considered; diagnoses of indefinite for dysplasia were excluded. Current guideline recommendations regarding the need for serial surveillance colonoscopy in patients with IBD were accepted, and other issues such as the appropriate surveillance interval or risk stratification 1-4,8-10 were not addressed.
Laine et al. (Fri,) studied this question.