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Fluorine can do it. Not only oxygen but also fluorine, covalently bonded in organic molecules, is an important donor atom in the coordination chemistry of biorelevant metal ions such as Na+, K+, Mg2+ and Ca2+. Clear evidence in favour of such interactions will be presented in this Minireview, followed by a discussion of possible implications for fluorinated, bioactive compounds.
Herbert Plenio (Wed,) studied this question.
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