The preparation of nanoparticles through sustainable chemical practices offers an eco-friendly and feasible route to advanced nanomaterials. In this study, gold nanoparticles (Au-NPs) were synthesized using Garcinia mangostana (GM) peel extract, which is rich in antioxidants and provides biomolecules acting as bio-reductants, capping, and stabilizing agents. The synthesized Au-NPs were characterized by X-Ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), UV–Vis spectroscopy, scanning electron microscopy (SEM), and photoluminescence (PL) spectroscopy. XRD confirmed the face-centered cubic structure of Au-NPs, while UV–Vis spectra exhibited a characteristic absorption peak around 540 nm. TEM images revealed polydispersed nanoparticles with diverse shapes and sizes. FTIR analysis indicated the presence of phenols, flavonoids, benzophenones, and anthocyanins, suggesting their role in the reduction and stabilization of Au-NPs. The catalytic activity of Au-NPs was demonstrated by the effective degradation of Fuchsin Basic dye, achieving up to 89% clearance efficiency under optimized conditions. Parameters such as catalyst dosage, scavenger activity, and the effect of electrolytes were systematically investigated. Furthermore, the Au-NPs exhibited significant antibacterial, antifungal, antioxidant, and cytotoxic activities, with pronounced cytotoxic effects against HepG2 cancer cells. Overall, the green-synthesized Au-NPs demonstrated excellent photocatalytic, antimicrobial, antioxidant, and anticancer properties, highlighting their potential for diverse applications in nano-biomedicine.
Selwyna et al. (Fri,) studied this question.