High trait anxiety, but not state anxiety, was significantly associated with biomarkers for hypertension including systolic blood pressure and pulse pressure in metabolic syndrome (SEM R2 = 0.998).
Cross-Sectional (n=101)
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Is self-reported anxiety associated with biomarkers for hypertension in patients with metabolic syndrome?
Trait anxiety, but not state anxiety, is associated with hypertension biomarkers including systolic blood pressure, pulse pressure, and total cholesterol in patients with metabolic syndrome.
Various studies link hypertension with anxiety; however, it remains unclarified if such relations are present in the metabolic syndrome (MetS). We studied cross-sectionally the interrelations of self-reported anxiety (Spielberger STAI), and MetS components in MetS patients. We investigated a nationally sampled treatment cohort for MetS with familial Type 2 diabetes risk. N = 101 patients fulfilling International Diabetes Federation criteria for MetS participated. Both laboratory and nonlaboratory measures were included. Structural equation models (SEM) were adjusted. The final SEM had an R(2) = .998 with the obesity component linking to waist, BMI, and degree of adiposity, and the hypertension component linking to systolic blood pressure, pulse pressure, total cholesterol, and trait anxiety. For state anxiety, no significant regressive causal path could be estimated. SEM supports the assumption of an interaction of pulse pressure, systolic blood pressure, cholesterol metabolism, and high trait anxiety in the pathophysiology of hypertension in MetS.
Lemche et al. (Wed,) conducted a cross-sectional in Metabolic syndrome (n=101). Self-reported anxiety assessment (Spielberger STAI) was evaluated on Interrelations of anxiety and metabolic syndrome components. High trait anxiety, but not state anxiety, was significantly associated with biomarkers for hypertension including systolic blood pressure and pulse pressure in metabolic syndrome (SEM R2 = 0.998).