COPD was associated with a significantly higher prevalence of multimorbidity compared to non-COPD individuals (91.38% vs 59.98%; adjusted OR 4.558, 95% CI 1.734-11.984).
Cross-Sectional (n=1,837)
COPD and multimorbidity have a strong bidirectional association in a health check-up population, highlighting the need for integrated management.
Estimación del efecto: adjusted OR 4.558 (95% CI 1.734-11.984)
Tasa de eventos absoluta: 91.38% vs 59.98%
Abstract Background Patients with Chronic Obstructive Pulmonary Disease (COPD) frequently suffer from multimorbidity. However, the risk of COPD patients developing comorbid conditions, and conversely, the risk of patients with other comorbidities developing COPD, remains unclear, especially within health check-up populations. Objective To investigate the distribution characteristics and the bidirectional risk relationship between COPD)and multimorbidity within a health check-up population. Methods In a cross-sectional study, data on 93 diseases were extracted from the health examination records of 1,837 individuals. Data were analyzed based on prevalence, sex, age, smoking status, and alcohol consumption. Multimorbidity was defined as the presence of two or more chronic conditions. Furthermore, logistic regression analyses were performed with the presence of COPD and the presence of multimorbidity as dependent variables, respectively, to assess the risk relationship between COPD and multimorbidity. Results In the study population, 82.53% (80.72-84.19) of individuals had one or more chronic diseases, and 60.97% (58.72-63.17) were identified with multimorbidity. The prevalence of multimorbidity increased substantially with age, reaching 90.91% (76.43-96.86) in individuals aged 60 years and older. The prevalence of multimorbidity among COPD patients was 91.38% (81.36-96.26), which was significantly higher than the 59.98% (57.68-62.23) observed in non-COPD individuals. The risk of having COPD increased with the number of comorbid conditions (unadjusted OR: 1.507, 95% CI: 1.348-1.684; adjusted OR: 1.433, 95% CI: 1.254-1.632). Conversely, patients with COPD had a 4.558-fold increased risk of having multimorbidity compared to those without COPD (unadjusted OR: 7.073, 95% CI: 2.814-17.781; adjusted OR: 4.558, 95% CI: 1.734-11.984). Conclusion In this cross-sectional study, COPD and multimorbidity demonstrated a strong bidirectional association. The risk of COPD increased with the number of comorbidities, while COPD itself was an independent risk factor, conferring a 4.5-fold increased risk for multimorbidity. These findings underscore the need for integrated management of COPD and its comorbidities. This abstract is funded by: None
Bao et al. (Fri,) conducted a cross-sectional in Chronic Obstructive Pulmonary Disease (COPD) (n=1,837). COPD vs. Non-COPD was evaluated on Presence of multimorbidity (two or more chronic conditions) (adjusted OR 4.558, 95% CI 1.734-11.984). COPD was associated with a significantly higher prevalence of multimorbidity compared to non-COPD individuals (91.38% vs 59.98%; adjusted OR 4.558, 95% CI 1.734-11.984).