Abstract Introduction Influenza vaccination remains a critical strategy to reduce morbidity and mortality from seasonal influenza. Contemporary, real-world data on uptake in diverse clinical populations are essential to guide targeted vaccination strategies. We examined influenza vaccination status and associated demographic factors in a multicenter sample of clinic patients during the 2024-2025 season. Methods Between September 1, 2024, and April 30, 2025, adult patients across multiple outpatient clinics were invited to share their influenza vaccination status. Institutional Review Board approval was obtained. Of 967 patients approached, 316 consented (response rate: 32.7%). Vaccination status was determined by documentation of vaccine receipt during the clinic visit or by patient self-report. Demographic, language, and insurance data were collected. Chi-Square and Fisher’s exact test was used for categorical analyses. Results Of the 316 participants, 245 (77.5%) were vaccinated and 71 (22.5%) were not. The median age category was 40-59 years (33.2%), with additional representation from 60-64 years (24.7%), 65-69 years (16.8%), and 70-74 years (14.6%). Females comprised 57.6% of participants. The cohort was racially diverse, with 51.1% African American, 36.2% White, and 12.7% identifying as other race; 9% identified as Hispanic. Insurance coverage was primarily commercial (39.1%), followed by Medicare (16.0%), none (20.8%), and other plans. Vaccination uptake increased with age, ranging from 61.5% in patients aged 30-39 to 84.8% in those aged 70-74. Prior influenza vaccination in 2023-2024 strongly predicted uptake in 2024-2025 (100% vs 14.3%; p 0.0001). Uptake was significantly higher among Hispanic compared with non-Hispanic participants (92.9% vs 76.4%; p = 0.03). Conclusion In this multicenter, clinic-based cohort, influenza vaccination uptake during the 2024-2025 season was 77.5%. Prior vaccination was associated with influenza vaccination, while disparities were observed by ethnicity This abstract is funded by: ATS Grant #: AW-100039-1/CC10105/FD260/PG20
Marouf et al. (Fri,) studied this question.