The Effect of Including 1 Avocado Daily in a Habitual Diet on the Glycemic Index and Glycemic Load in Free-Living Adults with Overweight/Obesity

Background: Few studies have explored the effect of a single-food intervention on the dietary glycemic index (GI) and glycemic load (GL) within the context of a habitual diet. Avocados are low in carbohydrates but rich in monounsaturated fatty acids, fiber, and other bioactive compounds. This raises the question of whether eating 1 avocado a day could lower the GI and GL of the diet, potentially reducing cardiometabolic risk. Objectives: This study aimed to assess whether adding 1 large avocado (168 g) daily for 6 mo to the habitual diet of adults with abdominal obesity reduces dietary GI and/or GL. Methods: This secondary analysis used data from the Habitual Diet and Avocado Trial, a multicenter, randomized, parallel-arm study involving 1008 adults with elevated waist circumference. Participants were randomly assigned to either an avocado-supplemented group, instructed to consume 1 large avocado daily with their usual diet, or a control group who maintained their habitual diet and avoided avocados. Dietary intake was assessed via 3 unannounced 24-h dietary recalls over the 6-mo period, from which dietary GI and GL were calculated using Nutrition Data System for Research software. Linear regression models adjusted for age, sex, BMI, energy intake, race, ethnicity, education level, and study site were used to evaluate between-group differences. Results: < 0.001) compared with the control. Food groups contributed similar amounts to the overall GL, except for avocado. Conclusions: Daily consumption of 1 avocado within the habitual diet significantly reduced GL by almost 14 points, without requiring significant dietary changes. This suggests that incorporating a single nutrient-dense food like avocado can effectively improve the GL simply and sustainably.This trial is registered at clinicaltrials.gov as NCT03528031.