Using the serratus anterior muscle as a reference region for T2-weighted images showed the strongest correlation with visual analysis of myocardial edema extent (r = 0.799; P < 0.001).
Observational (n=49)
Which skeletal muscle is the most reliable reference for calculating the T2 signal intensity ratio to quantify myocardial edema in acute MI?
The serratus anterior muscle is the most reliable and reproducible reference region for semiautomated quantification of myocardial edema on T2-weighted MRI in acute MI patients.
Estimación del efecto: r = 0.799
valor p: p=<0.001
OBJECTIVES: The purpose of our study was to identify the suitability of various skeletal muscles as reference regions for calculating the T2 SI ratio for a semiautomated quantification of the extent of myocardial edema with T2-weighted images. METHODS: Thirty-four patients with acute myocardial infarction (MI) were enrolled. The extent of myocardial edema was determined by T2 SI ratio map, using 4 different muscles as reference: major and minor pectoralis, serratus anterior, teres minor-infraspinatus, and subscapularis. The size of myocardial edema as visually quantified was used as the standard of truth. The control group consisted of 15 patients with chronic MI. Intra- and interobserver variability were assessed. RESULTS: Due to poor image quality four patients were excluded from the analysis. In acute MI patients, serratus anterior muscle showed the strongest correlation with the visual analysis (r = 0.799; P < 0.001) and low inter- and intraobserver variability, while the other muscles resulted in a significant interobserver variability. In contrast, the use of other muscles as a reference led to overestimating edema size. CONCLUSIONS: In acute MI patients, serratus anterior resulted to be the most reliable and reproducible muscle for measuring the extent of myocardial edema.
Carbone et al. (Thu,) conducted a observational in Acute myocardial infarction (n=49). Serratus anterior muscle reference vs. Other skeletal muscles (pectoralis, teres minor-infraspinatus, subscapularis) was evaluated on Correlation of T2 SI ratio map with visual quantification of myocardial edema size (r = 0.799, p=<0.001). Using the serratus anterior muscle as a reference region for T2-weighted images showed the strongest correlation with visual analysis of myocardial edema extent (r = 0.799; P < 0.001).