Combining DENSE and SENC MRI techniques successfully quantified 3D cardiac strain in healthy volunteers, yielding mean peak first, second, and third principal strains of 0.42, -0.10, and -0.21.
Cross-Sectional (n=6)
Can combining DENSE and SENC MRI techniques reliably quantify 3D cardiac strain in healthy volunteers?
Combining DENSE and SENC MRI techniques provides a reliable method for quantifying 3D myocardial strain.
Three-dimensional (3D) strain maps of the myocardium provide a coordinate-system-independent quantification of myocardial deformation and kinematics. We combine two MRI techniques, displacement encoding with stimulated echoes (DENSE) and strain encoding (SENC), to fully formulate a 3D strain map in a single slice of myocardium. The method utilizes 2D DENSE in-plane displacement measurements in two adjacent slices in conjunction with a single SENC through-plane strain measure to calculate the 3D strain tensor. Six volunteers were imaged and the technique demonstrated 3D strain measures in all volunteers that are consistent with those reported in the literature from 3D tagging. The mean peak strain (+/- standard deviation SD) for six healthy volunteers for the first, second, and third principal strains are 0.42 +/-0.11, -0.10 +/-0.03, and -0.21 +/-0.02, respectively. These results show that this technique is capable of reliably quantifying 3D cardiac strain.
Hess et al. (Wed,) conducted a cross-sectional in Healthy volunteers (n=6). Combined DENSE and SENC MRI was evaluated on Mean peak strain for the first, second, and third principal strains. Combining DENSE and SENC MRI techniques successfully quantified 3D cardiac strain in healthy volunteers, yielding mean peak first, second, and third principal strains of 0.42, -0.10, and -0.21.
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