July 15, 1997Open Access

Transcription Factors, Normal Myeloid Development, and Leukemia

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Resumen

TRANSCRIPTION FACTORS play a major role in differentiation in a number of cell types, including the various hematopoietic lineages.1-41 In the hematopoietic system, stem cells undergo a process of commitment to multipotential progenitors, which in turn give rise to mature blood cells. Although a

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Tenen et al. (Tue,) studied this question.

synapsesocial.com/papers/6a0ff44fb6f5ee0401602388 https://doi.org/https://doi.org/10.1182/blood.v90.2.489.489_489_519

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1A Novel Human CCAAT/Enhancer Binding Protein Gene, C/EBPϵ, Is Expressed in Cells of Lymphoid and Myeloid Lineages and Is Localized on Chromosome 14q11.2 Close to the T-Cell Receptor α/δ Locus1996 · 110 citations
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3Retinoic acid receptors and retinoid X receptor-alpha down-regulate the transforming growth factor-beta 1 promoter by antagonizing AP-1 activity1993 · 60 citations
4Double knockout of the ALL-1 gene blocks hematopoietic differentiation in vitro.1996 · 69 citations
5DNA binding specificities of Spi-1/PU.1 and Spi-B transcription factors and identification of a Spi-1/Spi-B binding site in the c-fes/c-fps promoter.1995 · 107 citations

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