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A deamination-driven biocatalytic cascade for the synthesis of ribose-1-phosphate | Synapse

January 1, 2024Open Access

A deamination-driven biocatalytic cascade for the synthesis of ribose-1-phosphate

JMJonas MotterTechnische Universität Berlin SWSarah WestarpTechnische Universität Berlin JBJonas BarsigHeinrich Heine University Düsseldorf

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Resumen

We present a sustainable biocatalytic process for the one-pot synthesis of Rib1P. By coupling a guanine deaminase to the nucleoside phosphorylase-catalysed Guo cleavage, the reaction was shifted towards almost complete Guo cleavage.

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Cite This Study

Motter et al. (Mon,) studied this question.

synapsesocial.com/papers/6a107e11e1a472cb5efd044c https://doi.org/https://doi.org/10.1039/d4gc02955k