Los puntos clave no están disponibles para este artículo en este momento.
We define a bootstrap sampling plan for the case-cohort design and present bootstrap variance estimates and confidence intervals for the log relative hazard. The coverages of these confidence intervals are found to be near nominal levels in simulations. A simple null variance calculation, based on a superpopulation model, is shown to provide good estimates of the power and efficiency of the case-cohort design.
Wacholder et al. (Sun,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: