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Conventional approaches to chemical sensors have made use of a “lock-and-key” design, a specific receptor is synthesized in order to and highly selectively bind the analyte of. 1-6 A related approach involves exploiting a physicochemical effect selectively toward a analyte, such as the use of the ionic effect in construction of a pH electrode. In the first, selectivity is achieved through recognition the analyte at the receptor site, and in the second, is achieved through the transduction in which the method of detection dictates species are sensed. Such approaches are appropriate a specific target compound is to be in the presence of controlled backgrounds interferences. However, this type of approach the synthesis of a separate, highly selective for each analyte to be detected. In addition, type of approach is not particularly useful for, classifying, or assigning human value to the composition of complex vapor such as perfumes, beers, foods, mixtures of, etc.
Albert et al. (Sat,) studied this question.