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September 1, 1944Journal of the American Statistical Association845 citations

Application of the Logistic Function to Bio-Assay

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JBJoseph Berkson

Key Points

  • To propose and evaluate the application of the logistic function as an analytical model for quantal response data in biological assays.
  • Evaluated the mathematical properties and curve-fitting techniques of the symmetric logistic function compared to integrated normal distribution models.
  • Formulated computational procedures for parameter estimation and dose-response curve fitting in bio-assay experiments.
  • Demonstrated that the logistic function provides an effective and computationally tractable framework for bio-assay data analysis.
  • Showed that logistic curve fitting yields parameter estimates comparable to normal probit analysis while substantially simplifying mathematical calculations.

Abstract

(1944). Application of the Logistic Function to Bio-Assay. Journal of the American Statistical Association: Vol. 39, No. 227, pp. 357-365.

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Cite This Study

Joseph Berkson (1944) studied this question.

synapsesocial.com/papers/6a10cde0cfa01e990d9f91a8https://doi.org/10.1080/01621459.1944.10500699
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