High brachial-ankle pulse wave velocity (≥1,400 cm/s) was significantly associated with early carotid atherosclerosis (OR 2.22) compared to normal velocity in a Japanese general male population.
Cross-Sectional (n=1,583)
Is high brachial-ankle pulse wave velocity associated with early carotid atherosclerosis in a general male population?
High brachial-ankle pulse wave velocity (>1,400 cm/s) is a stronger independent predictor of early carotid atherosclerosis than conventional risk factors like high blood pressure or dyslipidemia in a general male population.
Estimación del efecto: OR 2.22 (95% CI 1.24-4.17)
valor p: p=<0.01
BACKGROUND: Although there have been several reports on the risk factors associated with intima-media thickness (IMT), many questions remain. The purpose of this study was to investigate the association between IMT and cardiovascular risk factors in a Japanese general population. METHODS AND RESULTS: ), high BP (SBP ≥130 mmHg or DBP ≥85 mmHg), dyslipidemia (LDL-C ≥140 mg/dL, TG ≥150 mg/dL, or HDL-C <40 mg/dL), impaired fasting glucose (IFG) (fasting glucose ≥110 g/dL), and high baPWV (≥1,400 cm/s). Carotid atherosclerosis was significantly associated with only high baPWV (OR: 2.22, 95% CI: 1.24-4.17, P<0.01). CONCLUSIONS: High baPWV was a stronger predictor of early carotid atherosclerosis than high BP, dyslipidemia, or IFG in a Japanese general male population.
Kubozono et al. (Wed,) conducted a cross-sectional in Early carotid atherosclerosis (n=1,583). High brachial-ankle pulse wave velocity (baPWV ≥1,400 cm/s) vs. Normal baPWV (<1,400 cm/s) was evaluated on Carotid atherosclerosis (carotid IMT ≥1.0 mm) (OR 2.22, 95% CI 1.24-4.17, p=<0.01). High brachial-ankle pulse wave velocity (≥1,400 cm/s) was significantly associated with early carotid atherosclerosis (OR 2.22) compared to normal velocity in a Japanese general male population.