Repetitive reactive hyperemia over a 2-hour period had no significant effect on flow-mediated dilation measurements between treatment conditions (p=0.344).
RCT (n=20)
Randomized treatment days
Does repetitive reactive hyperemia affect brachial artery flow-mediated dilation measurements over a 2-hour period in healthy college students?
Repetitive reactive hyperemia over a 2-hour period does not significantly alter flow-mediated dilation measurements, supporting its stability for pre/post intervention assessments.
valor p: p=0.344
To capture the response of an acute intervention, multiple post intervention measurements of flow-mediated dilation (FMD) must be performed. The effect of repetitive reactive hyperemia on endothelial function and the measurement of FMD are unknown. The purpose of this investigation was (1) to examine the effect of repetitive reactive hyperemia on brachial artery FMD and (2) to determine whether brachial artery FMD is stable during a 2-h morning period. We investigated FMD in 20 apparently healthy college students on three randomized treatment days every 30 min (T30), 60 min (T60), and 120 min (T120) throughout a 2-h morning period (08.00 h to 10.00 h). An ANOVA (p > 0.05) and ICC (> 0.40) were both needed to confirm no difference among repetitive reactive hyperemia treatments. In response to repetitive reactive hyperemia, there was no difference (p = 0.307; ICC > 0.40) within the first and last FMD measurements of each treatment condition or between treatment conditions (p = 0.344; ICC > 0.40). FMD was similar (p = 0.348) throughout the 2-h morning period. In conclusion, repetitive reactive hyperemia over a 2-h period has no effect on FMD measurements in apparently healthy college students. In addition, this study found no time trends for FMD measurements during the 2-h morning period to allow for pre/post intervention FMD measurements.
Harris et al. (Wed,) conducted a rct in Healthy (n=20). Repetitive reactive hyperemia vs. Different frequencies of reactive hyperemia (every 30, 60, or 120 min) was evaluated on Brachial artery flow-mediated dilation (FMD) (p=0.344). Repetitive reactive hyperemia over a 2-hour period had no significant effect on flow-mediated dilation measurements between treatment conditions (p=0.344).