A computational model demonstrated that decreased tissue permeability and increased red blood cell velocity reduce resistance to blood flow in narrow capillaries.
This work focuses on how blood move between tiny blood vessels (capillaries) and surrounding tissues, especially when the capillary diameter is smaller than that of red blood cells (RBCs). It has shown that in such narrow vessels, there is very little space between the RBC and the vessel wall, allowing plasma to squeeze through. It is shown in this work at how different factors like the shape of deformed RBCs, their speed, and how easily tissues allow fluids to pass (permeability) affect the flow of blood. It has also shown that when tissues are less permeable, blood flow is smoother. Also, faster-moving RBCs encounter less resistance. By comparing its findings with other models, this study demonstrates its value in understanding blood flow dynamics in small vessels. This knowledge could lead to the development of new diagnostic tools for various diseases.
Jaiswal et al. (Mon,) conducted a other in Microcirculation fluid dynamics. Computational modeling of red blood cell deformation was evaluated on Resistance to flow. A computational model demonstrated that decreased tissue permeability and increased red blood cell velocity reduce resistance to blood flow in narrow capillaries.
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