T1 mapping with cardiac magnetic resonance provides a quantitative method to evaluate myocardial extracellular volume fraction and characterize diffuse myocardial diseases such as fibrosis.
T1 mapping is a promising CMR technique for quantitative evaluation of myocardial tissue, overcoming limitations of traditional late gadolinium enhancement in detecting diffuse myocardial disease.
Magnetic resonance as an imaging modality provides an excellent soft tissue differentiation, which is an ideal choice for cardiac imaging. Cardiac magnetic resonance (CMR) allows myocardial tissue characterization, as well as comprehensive evaluation of the structures. Although late gadolinium enhancement after injection of the gadolinium extracellular contrast agent has further extended our ability to characterize the myocardial tissue, it also has limitations in the quantification of enhanced myocardial tissue pathology, and the detection of diffuse myocardial disease, which is not easily recognized by enhancement contrast. Recently, the remarkable advances in CMR technique, such as T1 mapping, which can quantitatively evaluate myocardial status, showed potentials to overcome limitations of existing CMR sequences and to expand the application of CMR. This article will review the technical and clinical points to be considered in the practical use of pre-and post-contrast T1 mapping. (
Hwang et al. (Tue,) conducted a review in Myocardial disease. T1 mapping (Cardiac Magnetic Resonance) was evaluated. T1 mapping with cardiac magnetic resonance provides a quantitative method to evaluate myocardial extracellular volume fraction and characterize diffuse myocardial diseases such as fibrosis.
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