Triple vessel coronary artery disease (OR 5.71), normothermic systemic perfusion (OR 4.85), and age >70 years (OR 3.88) were the strongest independent predictors of stroke following CABG.
Cohort (n=3,910)
No
Identifies key preoperative risk factors for stroke after CABG, highlighting the need for targeted preventive strategies in high-risk patients.
Estimación del efecto: OR 5.71
Improvements in surgical technique and advances in myocardial protection have resulted in low rates of morbidity and mortality despite a greater incidence of high-risk patients. Noncardiac morbidity prolongs hospital stays and increases the costs of cardiac surgery. This study examines the preoperative predictors of stroke following isolated coronary bypass surgery. The clinical records of 3910 consecutive patients who underwent isolated coronary bypass surgery at the University of Toronto were reviewed. Stepwise logistic regression identified six independent predictors of stroke following CABG (percent in parentheses) and calculated factor adjusted odds ratios (OR) for each risk factor. Triple vessel coronary artery disease was the most important predictor (1.9%, OR 5.71), followed by normothermic systemic perfusion (3.8%, OR 4.85), age > 70 years (3.2%, OR 3.88), a previous history of transient ischemic attacks or stroke prior to surgery (6.1%, OR 3.7), peripheral vascular disease (4.7%, OR 2.77), and diabetes mellitus (2.6%, OR 2.01). The mechanism of stroke is likely different between these high-risk groups and strategies to prevent postoperative stroke should focus on the mechanisms responsible in high-risk patients.
Rao et al. (Sat,) conducted a cohort in Coronary bypass surgery (n=3,910). Risk factors for stroke post-CABG was evaluated on Stroke following CABG (OR 5.71). Triple vessel coronary artery disease (OR 5.71), normothermic systemic perfusion (OR 4.85), and age >70 years (OR 3.88) were the strongest independent predictors of stroke following CABG.