Abnormally high preoperative C-reactive protein levels (>0.5 mg/dL) independently predicted very late recurrence of atrial fibrillation after catheter ablation (HR 4.9; 95% CI 2.3-10.7; P<0.0001).
Cohort (n=392)
No
Estimación del efecto: HR 4.9 (95% CI 2.3-10.7)
valor p: p=< 0.0001
AIMS: Although several prognostic factors for atrial fibrillation (AF) recurrence after catheter ablation (CA) have been reported, predictors of very late recurrence (VLR; initial recurrence >12 months after ablation) remain unidentified. This study investigated clinical variables predictive of VLR after CA for AF. METHODS AND RESULTS: This retrospective single-centre cohort study evaluated data from 1016 consecutive drug-refractory AF patients who underwent single CA for AF from July 2004 to May 2010. After excluding 324 patients with a short follow-up period (0.5 mg/dL (HR 4.28, 95% CI 2.03-9.03, P < 0.0001) were associated with VLR. In the multivariate model, only abnormally high preoperative CRP level was an independent predictor of VLR (HR 4.9, 95% CI 2.3-10.7, P < 0.0001). CONCLUSION: Even after a year without AF, VLR occurred annually in 7.6% cases. Continued vigilance for VLR after CA is clinically desirable, especially for patients with abnormally high preoperative CRP levels.
Sotomi et al. (Sun,) conducted a cohort in Atrial fibrillation (n=392). Abnormally high preoperative C-reactive protein (CRP) levels >0.5 mg/dL was evaluated on Very late recurrence (VLR) of atrial fibrillation (HR 4.9, 95% CI 2.3-10.7, p=< 0.0001). Abnormally high preoperative C-reactive protein levels (>0.5 mg/dL) independently predicted very late recurrence of atrial fibrillation after catheter ablation (HR 4.9; 95% CI 2.3-10.7; P<0.0001).
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