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January 1, 2013Nigerian Journal of Basic and Clinical Sciences10 citations

Effect of interval training program on rate-pressure product in the management of hypertension in black African male subjects: A randomized controlled trial

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SLSikiru LaminaGOGoddyC OkoyeTATheresaI Anele

Key Result

An 8-week moderate intensity interval training program significantly improved rate-pressure product and VO2 max compared to remaining sedentary in black African men with essential hypertension.

Study Design

Type

RCT (n=245)

Structured PICO

Does an interval training program improve rate-pressure product in black African male subjects with essential hypertension?

P
Population
245 black African male patients with essential hypertension (mild to moderate systolic blood pressure between 140 and 179 mmHg and diastolic blood pressure between 90 and 109 mmHg)
I
Intervention
8-week interval training program (work:rest ratio of 1:1) of between 45 and 60 min at intensities of 60-79% of the maximum heart rate
C
Comparator
Remained sedentary during the 8-week period
O
Outcome
Rate-pressure productsurrogate

An 8-week moderate intensity interval training program significantly improves rate-pressure product and VO2 max in black African men with essential hypertension, serving as an effective non-pharmacological adjunct therapy.

Abstract

Background: Rate-pressure product is a determinant of cardiovascular risk in patient with hypertension and one of the major predictors of myocardial oxygen consumption. Aim: The primary purpose of the present study was to investigate the effect of interval training program on rate-pressure product in subjects with hypertension. Materials and Methods: Two hundred and forty-five male patients of essential hypertension with mild to moderate systolic blood pressure between 140 and 179 mmHg and diastolic blood pressure between 90 and 109 mmHg were age-matched and grouped into interval group ( n = 140) and control group ( n = 105). The interval (work:rest ratio of 1:1) group was involved in an 8-week interval training program of between 45 and 60 min at intensities of 60-79% of the maximum heart rate, while the control group remained sedentary during this period. Blood pressure, maximum volume of oxygen consumed (VO 2 max), and rate-pressure product were assessed. Results: Findings of the study revealed significant effect of exercise training program on rate-pressure product and VO 2 max. The correlation of rate-pressure product with systolic blood pressure was much stronger (87% variance) at P < 0.05. Conclusion: It was concluded that moderate intensity interval training program is an effective means of lowering myocardial oxygen consumption and an adjunct non-pharmacological management of essential hypertension.

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Cite This Study

Lamina et al. (2013) conducted an RCT in essential hypertension (n=245). interval training program vs. sedentary control was evaluated on rate-pressure product. An 8-week moderate intensity interval training program significantly improved rate-pressure product and VO2 max compared to remaining sedentary in black African men with essential hypertension.

synapsesocial.com/papers/6a12a0a592637892a9a6f1fchttps://doi.org/10.4103/0331-8540.117236
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