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Ashcroft, M. T. (Medical Research Council Epidemiological Research Unit, University of the West Indies, Kingston 7, Jamaica), W. E Miall and P. F. Milner. A comparison between the characteristics of Jamaican adults with normal hemoglobin and those with sickle cell trait. Amer. J. Epid., 1969, 90: 236–243.—In surveys of representative samples of Jamaicans aged 35–64 years living in rural and suburban communities, no significant differences in heights, weights, hema-tological indices, cardiothoracic ratios, blood pressures, glycosuria, proteinuria, parity or electrocardiographic abnormalities were apparent between 167 subjects with the sickle cell trait, AS, and 1, 282 subjects with normal hemoglobin, AA. Older women with the trait had a significantly higher prevalence of bacte-riuria without other evidence of urinary tract pathology. The findings suggest that the trait is not appreciably associated with chronic disease.
Ashcroft et al. (Mon,) studied this question.