May 20, 2017Open Access

Comparison of High Intensity Interval to Moderate Intensity Continuous Aerobic Exercise on Ventilatory Markers in Coronary Heart Disease Patients: A Randomized Controlled Study

Q: What is the clinical evidence from this study?

Study design: RCT. Population: Coronary Heart Disease (n=28). Intervention: High intensity interval exercise (HII) vs. Moderate intensity continuous aerobic exercise (MIC). Primary outcome: Change in oxygen pulse (O2P) (p=<0.05).

Q: What does this research mean for the field?

High intensity interval exercise significantly improves oxygen pulse by 21% compared to a 1% change with moderate intensity continuous exercise in patients with coronary heart disease. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Resultado clave

High intensity interval exercise significantly improved oxygen pulse by 21% compared to a 1% change with moderate intensity continuous exercise in patients with coronary heart disease.

Diseño del estudio

Tipo

RCT (n=28)

Enmascaramiento

Single-blind

Aleatorización

Randomized

Multicéntrico

PICO estructurado

Does high intensity interval exercise improve ventilatory markers compared to moderate intensity continuous exercise in patients with mild to moderate coronary heart disease?

Población

28 patients with mild to moderate coronary heart disease (CHD), aged 50-60 years, ejection fraction >50%. Excluded: acute myocardial infarction or revascularization (<90 days), pacemakers, heart failure, musculoskeletal limitations, and changes in medication. Selected from the cardiac rehabilitation unit, Cairo University Hospitals.

Intervención

High intensity interval (HII) treadmill aerobic exercise, 3 times/week for 12 weeks. Protocol: 5 minutes warm up, 30 minutes of HII (interchanging 60% maxHR and 90% maxHR workloads every 2 minutes).

Comparador

Moderate intensity continuous (MIC) treadmill aerobic exercise, 3 times/week for 12 weeks. Protocol: 5 minutes warm up, 30 minutes of continuous aerobic exercise at 70 to 75% of peak HR, and 5 minutes cool down.

Resultado

Ventilatory markers (peak VO2, slope of VE/VCO2, OUES, and O2P) measured by cardiopulmonary exercise test at 12 weeks.surrogate

High intensity interval exercise significantly improves peak VO2 and oxygen pulse compared to moderate intensity continuous exercise in patients with mild to moderate coronary heart disease.

Resultado numérico

Tasa de eventos absoluta: 21% vs 1%

valor p: p=<0.05

Limitaciones

Small sample size
Included patients with only mild or moderate CHD
High baseline ejection fraction (approximately 63%) may have influenced the effects of exercise on ventilatory variables
Lack of additional ventilatory variables for ventricular function, lung perfusion, and arterial blood gases to determine underlying mechanisms

Resumen

Objectives: This study aim was to compare the impacts of high intensity interval (HII) to moderate intensity continuous exercise (MIC) on ventilatory markers in patients with coronary heart disease (CHD).

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Cite This Study

Abdelbasset et al. (Sat,) conducted a rct in Coronary Heart Disease (n=28). High intensity interval exercise (HII) vs. Moderate intensity continuous aerobic exercise (MIC) was evaluated on Change in oxygen pulse (O2P) (p=<0.05). High intensity interval exercise significantly improved oxygen pulse by 21% compared to a 1% change with moderate intensity continuous exercise in patients with coronary heart disease.

synapsesocial.com/papers/6a12cfd18f1bac20a09e571f https://doi.org/https://doi.org/10.16965/ijpr.2017.126

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