An active standing test established diagnostic thresholds for POTS (ΔHR ≥38 bpm or max HR ≥130/125 bpm) and OHT (ΔSBP ≥20 mm Hg or ΔDBP ≥25/20 mm Hg) in children and adolescents.
Cross-Sectional (n=1,449)
Sí
What are the normative upright heart rate and blood pressure changes during an active standing test in Chinese children and adolescents?
The study provides normative data for heart rate and blood pressure changes during active standing in Chinese children, proposing specific diagnostic thresholds for POTS and orthostatic hypertension.
OBJECTIVE: We aimed to determine upright heart rate and blood pressure (BP) changes to suggest diagnostic criteria for postural orthostatic tachycardia syndrome (POTS) and orthostatic hypertension (OHT) in Chinese children. METHODS: In this cross-sectional study, 1449 children and adolescents aged 6-18 years were randomly recruited from two cities in China, Kaifeng in Henan province and Anguo in Hebei province. They were divided into two groups: 844 children aged 6-12 years (group I) and 605 adolescents aged 13-18 years (group II). Heart rate and BP were recorded during an active standing test. RESULTS: 95th percentile (P(95)) of δ heart rate from supine to upright was 38 bpm, with a maximum upright heart rate of 130 and 124 bpm in group I and group II, respectively. P(95) of δ systolic blood pressure (SBP) increase was 18 mm Hg and P(95) of upright SBP was 132 mm Hg in group I and 138 mm Hg in group II. P(95) of δ diastolic blood pressure (DBP) increase was 24 mm Hg in group I and 21 mm Hg in group II, and P(95) of upright DBP was 89 mm Hg in group I and 91 mm Hg in group II. CONCLUSIONS: POTS is suggested when δ heart rate is ≥ 38 bpm (for easy memory, ≥ 40 bpm) from supine to upright, or maximum heart rate ≥ 130 bpm (children aged 6-12 years) and ≥ 125 pm (adolescents aged 13-18 years), associated with orthostatic symptoms. OHT is suggested when δ SBP (increase) is ≥ 20 mm Hg, and/or δ DBP (increase) ≥ 25 mm Hg (in children aged 6-12 years) or ≥ 20 mm Hg (in adolescents aged 13-18 years) from supine to upright; or upright BP ≥ 130/90 mm Hg (in children aged 6-12 years) or ≥ 140/90 mm Hg (in adolescents aged 13-18 years).
Zhao et al. (Fri,) conducted a cross-sectional in Postural orthostatic tachycardia syndrome (POTS) and orthostatic hypertension (OHT) (n=1,449). Active standing test was evaluated on Upright heart rate and blood pressure (BP) changes. An active standing test established diagnostic thresholds for POTS (ΔHR ≥38 bpm or max HR ≥130/125 bpm) and OHT (ΔSBP ≥20 mm Hg or ΔDBP ≥25/20 mm Hg) in children and adolescents.