The newly defined CHA2DS2-VASC-HSF score demonstrated a statistically significant positive correlation with coronary artery disease severity assessed by Syntax score in 50 patients with NSTEMI.
Observational (n=50)
Does the CHA2DS2-VASc-HSF score correlate with the severity of coronary artery disease in patients with NSTEMI?
The newly defined CHA2DS2-VASC-HSF score correlates positively with the Syntax score, suggesting it can serve as a predictor for the severity of atherosclerosis in patients with NSTEMI.
Background: CHADS2 and CHA2DS2-VASc scores are widely used in clinical practice and include similar risk factors for the development of coronary artery disease (CAD). It is known that factors comprising the newly defined CHA2DS2-VASC-HSF score promote atherosclerosis and are associated with severity of CAD 1. Aim: To investigate the association of CHA2DS2-VASc-HSF score with severity of Coronary Artery Disease as assessed by Syntax Score (SxS) in patients with Non ST Segment Elevation Myocardial Infarction. Subjects and methods: A total of 50 patients with NSTEMI (37 males and 13 females, their age ranged from 35 to 77 years old with a mean age of 57.8 years old) who underwent coronary angiography were included in our study. The patients were divided into 2 groups according to SxS score (SxS ≤22 and SxS < 22(. Results: This study showed a statistically significant positive correlation between CHA2DS2-VASC-HSF score and Syntax score I of patients. There is a statistically significant positive correlation between CHA2DS2-VASC-HSF score and serum cholesterol levels of patients. A statistically significant positive correlation was found between CHA2DS2-VASC-HSF score and serum LDL levels of patients. Our study also showed a statistically significant negative correlation between CHA2DS2-VASC-HSF score and ejection fraction (EF%) of patients. Conclusions: A newly defined CHA2DS2-VASC-HSF score predicts the severity of atherosclerosis in patients with NSTEMI.
Al-shorbagy et al. (Sun,) conducted a observational in Non ST Segment Elevation Myocardial Infarction (NSTEMI) (n=50). CHA2DS2-VASc-HSF score was evaluated on Severity of Coronary Artery Disease as assessed by Syntax Score (SxS). The newly defined CHA2DS2-VASC-HSF score demonstrated a statistically significant positive correlation with coronary artery disease severity assessed by Syntax score in 50 patients with NSTEMI.