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October 24, 1996New England Journal of Medicine235 citations

Advances in Coronary Angioplasty

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JBJohn A. BittlInterventional Cardiology

Key Points

  • Review the therapeutic efficacy, procedural risks, and clinical advancements of coronary angioplasty, including the roles of stenting and glycoprotein IIb/IIIa receptor blockers in coronary artery disease.
  • Synthesized data from clinical trials examining interventional outcomes following coronary angioplasty.

Structured PICO

What are the recent advances in coronary angioplasty, including stents and glycoprotein IIb/IIIa inhibitors, for patients with coronary artery disease?

P
Population
Patients with coronary artery disease
I
Intervention
Coronary angioplasty, coronary stents, and blockers of platelet glycoprotein IIb/IIIa receptors
O
Outcome
Alleviation of symptoms of angina and reduction in the risk of death or nonfatal myocardial infarction

This review highlights advances in coronary angioplasty, including the use of stents and glycoprotein IIb/IIIa inhibitors to reduce acute complications and restenosis.

Abstract

The goal of therapy in patients with coronary artery disease is to alleviate symptoms of angina and reduce the risk of death or nonfatal myocardial infarction. Although coronary angioplasty immediately reduces anginal symptoms in almost all patients who undergo it, its use is associated with death or nonfatal myocardial infarction in about 5 percent of patients18 and with restenosis requiring repeated angioplasty or bypass surgery in about 30 percent.36,9 Recently, several clinical trials have shown that the implantation of coronary stents5,6 or treatment with blockers of platelet glycoprotein IIb/IIIa receptors1012 reduces the occurrence of acute . . .

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Cite This Study

John A. Bittl (1996) studied this question.

synapsesocial.com/papers/6a1546a5b2e0231f15823576https://doi.org/10.1056/nejm199610243351707
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