Limiting radiofrequency power to 20-25 W at specific parts of the posterior left atrium significantly reduced symptomatic gastric hypomotility compared to 25-30 W (0% vs 7.9%; P<0.0001).
Cohort (n=535)
Does limiting radiofrequency power to 20-25 W at the posterior left atrium reduce symptomatic periesophageal vagal nerve injury in patients undergoing pulmonary vein antrum isolation?
Titrating radiofrequency energy to 20-25 W where the ablation line transverses the esophagus significantly reduces the risk of periesophageal vagal nerve injury during pulmonary vein antrum isolation.
Tasa de eventos absoluta: 0% vs 7.9%
valor p: p=<0.0001
BACKGROUND: Periesophageal vagal nerve injury is recognized as a rare complication in atrial fibrillation ablation procedures. We investigated the factors associated with the occurrence of symptomatic periesophageal vagal nerve injury after pulmonary vein antrum isolation. METHODS AND RESULTS: Overall, 535 consecutive patients who underwent sole pulmonary vein antrum isolation were included. Point-by-point radiofrequency applications were applied using irrigated-tip catheters under minimal sedation without esophageal temperature monitoring. In the initial 165 patients, the ablation settings for the posterior left atrium were a maximum energy of 25 to 30 W and a duration of 30 seconds. In the subsequent 370 patients, the power was additionally limited to 20 to 25 W at specific parts of the posterior left atrium where the ablation line transversed the esophagus. Symptomatic gastric hypomotility was found in 13 patients, and all were observed during the initial period (7.9%). No other collateral damage was observed. Logistic regression analysis revealed that the body mass index was the only independent predictor for identifying patients with gastric hypomotility (odds ratio 0.770; 95% confidence interval 0.643 to 0.922; P=0.0045) during the initial period. The prevalence of gastric hypomotility was significantly higher in the initial study period than subsequently (0 of 370, 0%; P<0.0001). All except for 1 patient recovered completely with conservative treatment within 4 months after the procedure. CONCLUSIONS: Periesophageal vagal nerve injury is more common collateral damage than direct esophageal injury in pulmonary vein antrum isolation procedures. Titrating the radiofrequency energy at specific areas where the ablation line transverses the esophagus and taking account of the body mass index might reduce occurrences not only of direct esophageal damage but also of periesophageal vagal nerve injury in pulmonary vein antrum isolation procedures.
Miyazaki et al. (Tue,) conducted a cohort in Atrial fibrillation (n=535). Power-limited radiofrequency ablation vs. Standard power ablation (25-30 W) was evaluated on Symptomatic gastric hypomotility (p=<0.0001). Limiting radiofrequency power to 20-25 W at specific parts of the posterior left atrium significantly reduced symptomatic gastric hypomotility compared to 25-30 W (0% vs 7.9%; P<0.0001).
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