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December 1, 1984Biometrics

Random-Effects Models for Serial Observations with Binary Response

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Authors

RSRobert G. StiratelliNLNan M. LairdJWJames H. Ware

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Overview

Randomized trial demonstrates a novel method for analyzing serial binary responses, suggesting improved data utilization.

Key Points

  • The aim is to develop a mixed model for analyzing serial binary responses from participants.
  • Implemented a mixed model with varying logistic regression coefficients for each subject.
  • Used maximum likelihood estimation for fixed effects and variance components.
  • Compared the proposed method with the Korn and Whittemore two-step estimation strategy.
  • Demonstrated that the new method can utilize all available data, including incomplete cases.
  • Showed improvements in estimation despite increased computational complexity.
  • Exact solutions are infeasible; employed an approximation based on the posterior distribution.

Cite This Study

Stiratelli et al. (1984) studied this question.

synapsesocial.com/papers/6a155f4d0c3a39952e9f6ae2https://doi.org/10.2307/2531147
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