Body mass index was not significantly associated with 1-year all-cause mortality (HR 0.70; 95% CI 0.48-1.02) or cardiac-specific mortality (HR 1.11; 95% CI 0.64-1.92) after adjusting for confounders.
Observational (n=8,079)
Does higher BMI increase 1-year all-cause or cardiac-specific mortality in patients referred for coronary angiography?
In patients referred for coronary angiography, BMI was not independently associated with 1-year all-cause or cardiac-specific mortality after adjusting for confounding variables.
Estimación del efecto: HR 0.70 (95% CI 0.48-1.02)
Background and Aim . Obesity is associated with an increased risk of cardiovascular disease and may be associated with more severe coronary artery disease (CAD); however, the relationship between body mass index BMI (kg/m 2 ) and CAD severity is uncertain and debatable. The aim of this study was to examine the relationship between BMI and angiographic severity of CAD. Methods . Duke Jeopardy Score (DJS), a prognostic tool predictive of 1-year mortality in CAD, was assigned to angiographic data of patients ≥18 years of age (N=8,079). Patients were grouped into 3 BMI categories: normal (18.5–24.9 kg/m 2 ), overweight (25.0–29.9 kg/m 2 ), and obese (≥30 kg/m 2 ); and multivariable adjusted hazard ratios for 1-year all-cause and cardiac-specific mortality were calculated. Results . Cardiac risk factor prevalence (e.g., diabetes, hypertension, and hyperlipidemia) significantly increased with increasing BMI. Unadjusted all-cause and cardiac-specific 1-year mortality tended to rise with incremental increases in DJS, with the exception of DJS 6 (p0.001). After adjusting for potential confounders, no significant association of BMI and all-cause (HR 0.70, 95% CI .48–1.02) or cardiac-specific (HR 1.11, 95% CI .64–1.92) mortality was found. Conclusions . This study failed to detect an association of BMI with 1-year all-cause or cardiac-specific mortality after adjustment for potential confounding variables.
Gregory et al. (Sun,) conducted a observational in Coronary Artery Disease (n=8,079). Body Mass Index vs. Normal BMI (18.5-24.9 kg/m2) was evaluated on 1-year all-cause mortality (HR 0.70, 95% CI 0.48-1.02). Body mass index was not significantly associated with 1-year all-cause mortality (HR 0.70; 95% CI 0.48-1.02) or cardiac-specific mortality (HR 1.11; 95% CI 0.64-1.92) after adjusting for confounders.