Patients with portopulmonary hypertension exhibited less severe right ventricular enlargement compared to those with idiopathic pulmonary arterial hypertension (RVEDVI 89 vs 128 ml/m2; p=0.04).
Observational (n=28)
Do cardiac configuration and pulmonary vascular changes differ between patients with portopulmonary hypertension and idiopathic pulmonary arterial hypertension?
Patients with portopulmonary hypertension exhibit more moderate right ventricular remodeling and pulmonary vascular changes compared to those with idiopathic pulmonary arterial hypertension.
Tasa de eventos absoluta: 89% vs 128%
valor p: p=0.04
BACKGROUND: The goal of the present study was to examine the cardiac configuration and pulmonary vascular changes in patients with portopulmonary hypertension (PPHTN) and compare them with those of idiopathic pulmonary arterial hypertension (IPAH). METHODS AND RESULTS: The subjects were 10 patients with PPHTN and 18 with IPAH. In PPHTN, the increases in the right ventricular end-diastolic volume index (89+/-19 vs 128+/-50 ml/m2; p=0.04), right end-systolic volume index (50+/-19 vs 95+/-47 ml/m 2; p=0.02) and right ventricular mass index (47+/-18 g/m2 vs 79+/-31; p=0.04) were low compared with IPAH. The decrease in the right ventricular ejection fraction was also low in PPHTN (45+/-10 vs 28+/-13%; p=0.01). The degree of sparse arborization and abrupt narrowing on wedged pulmonary angiography was moderate in PPHTN compared with IPAH. In PPHTN, the proximal pulmonary arteries were dilated near the segmental arteries, which were narrow in IPAH. CONCLUSION: Changes in the configuration of the heart were moderate in PPHTN compared with those in IPAH. The degree of sparse arborization and abrupt narrowing were also moderate in PPHTN.
Sakuma et al. (Sat,) conducted a observational in Portopulmonary hypertension and idiopathic pulmonary arterial hypertension (n=28). Portopulmonary hypertension (PPHTN) vs. Idiopathic pulmonary arterial hypertension (IPAH) was evaluated on Right ventricular end-diastolic volume index (ml/m2) (p=0.04). Patients with portopulmonary hypertension exhibited less severe right ventricular enlargement compared to those with idiopathic pulmonary arterial hypertension (RVEDVI 89 vs 128 ml/m2; p=0.04).