In 22 normal subjects, changes in blood pressure variability in response to psychological stressors were inversely related to resting heart period variability.
Observational (n=22)
Blood pressure exhibits variability (BPV) at low (0.02- to 0.07-Hz), mid (0.07- to 0.15-Hz)-, and high (0.15- to 0.50-Hz) frequencies. Evidence suggests that BPV responses to challenge are inversely related to cardiac autonomic control. We tested this hypothesis by examining the BPV responses to psychological stressors in 22 normal subjects who differed in cardiac control, operationalized as resting heart period variability (HPV). HPV and BPV were measured noninvasively or a beat-to-beat basis. The stressors produced a significant increase in heart rate and a small but significant increase in diastolic blood pressure. As predicted, the changes in BPV in response to the stressors were inversely related to resting HPV. The results are interpreted in terms of a model of cardiovascular control that holds that BPV originates from feedforward effects of central control of the heart, feedback effects mediated through the baroreflexes, and direct sympathetic vascular effects.
Sloan et al. (Thu,) conducted a observational in Healthy subjects (n=22). Psychological stressors vs. Resting state was evaluated on Blood pressure variability (BPV) responses to psychological stressors. In 22 normal subjects, changes in blood pressure variability in response to psychological stressors were inversely related to resting heart period variability.
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