Left atrial strain rate during atrial contraction (LASRa) was the strongest echocardiographic predictor of pulmonary capillary wedge pressure, with a value ≤0.9 1/s demonstrating 88% accuracy in predicting pressures >15 mmHg.
Observational (n=144)
No
Does left atrial strain rate during atrial contraction (LASRa) accurately predict elevated pulmonary capillary wedge pressure in symptomatic patients?
Left atrial strain rate during atrial contraction is a strong echocardiographic predictor of elevated pulmonary capillary wedge pressure, outperforming conventional uni- and multi-variable models.
Estimación del efecto: r2 = 0.40
valor p: p=<0.001
Abstract This study aimed to assess the relationship between different LA strain components and PCWP as well as to the relationship with other established methods. We studied 144 symptomatic patients, age 63 ± 14 years, 54 males, using conventional transthoracic echocardiography protocols, including LA and LV myocardial deformation from speckle tracking technique investigations along with simultaneous right heart catheterization (RHC) using established techniques. From RHC, pulmonary artery pressure (PAP), and pulmonary capillary wedge pressure (PCWP) were measured and pulmonary vascular resistance (PVR) calculated. LA strain rate during atrial contraction (LASRa) was the strongest correlate with PCWP (r 2 = − 0.40, p 34 ml/m 2 (r 2 = 0.60, p 15 mmHg which was superior to recently proposed uni- and multi-variable models. LASR during atrial contraction is the strongest predictor of PCWP, particularly in patients with post-capillary PH and with dilated LA cavity. Furthermore, it proved superior to recently proposed uni- and multi-variable based algorithms. Its close relationship with LV strain rate counterpart reflects important left heart chamber interaction in patients with raised LA pressure.
Lindqvist et al. (Sun,) conducted a observational in Suspected pulmonary hypertension or heart failure (n=144). Left atrial strain rate during atrial contraction (LASRa) vs. Other echocardiographic parameters (LASRs, LASs, E/e', multi-variable models) was evaluated on Correlation between LASRa and pulmonary capillary wedge pressure (PCWP) (r2 = 0.40, p=<0.001). Left atrial strain rate during atrial contraction (LASRa) was the strongest echocardiographic predictor of pulmonary capillary wedge pressure, with a value ≤0.9 1/s demonstrating 88% accuracy in predicting pressures >15 mmHg.