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Reply to Zhao et al .: Clarifying Structural – Functional Coupling by FeNO Status in VESTIGE | Synapse
May 29, 2026
Reply to Zhao et al .: Clarifying Structural – Functional Coupling by FeNO Status in VESTIGE
ED
Eleanor M Dunican
MC
Mario Castro
AP
Alberto Papi
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Puntos clave
This research aims to clarify the relationship between structural and functional coupling based on FeNO status.
Discussed findings and interpretations from Zhao et al.
Analyzed implications of FeNO as a biomarker in functional assessments
Provided insights on the VESTIGE cohort's structural-functional dynamics
Clarified misconceptions regarding the interpretation of FeNO status in structural-functional coupling.
Highlighted the relevance of FeNO as a significant biomarker in assessing lung function.
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International audience
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Dunican et al. (Fri,) studied this question.
synapsesocial.com/papers/6a192c0ffab5b468c44150bb
https://doi.org/https://doi.org/10.1093/ajrccm/aamag221