A 64-year-old female with severe calcium channel blocker overdose developed refractory cardiogenic shock and multi-organ failure, ultimately passing away despite aggressive multimodal therapy.
Case Report (n=1)
No
Severe calcium channel blocker overdose can present with cardiogenic shock requiring advanced multimodal pharmacological interventions.
Calcium channel blocker (CCB) overdose is a rare but potentially life-threatening presentation associated with profound bradycardia, shock, and metabolic disturbances. Management can be complex, often requiring advanced hemodynamic support and multimodal therapies. We report a case of severe CCB intoxication leading to refractory hypotension, illustrating the challenges encountered in critical care management. Current approaches involve multimodal pharmacological interventions, including high-dose insulin euglycemic therapy, IV calcium, glucagon, and lipid rescue. CCBs have widespread use; therefore, understanding the consequences of overdose is clinically important.
Adedolapo V Adejumo (Tue,) conducted a case report in Calcium channel blocker overdose with cardiogenic shock (n=1). Multimodal therapy (high-dose insulin euglycemic therapy, glucagon, IV calcium, vasopressors) was evaluated on Patient survival. A 64-year-old female with severe calcium channel blocker overdose developed refractory cardiogenic shock and multi-organ failure, ultimately passing away despite aggressive multimodal therapy.
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